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Alcohol Relapse Induced by Discrete Cues Activates Components of AP-1 Transcription Factor and ERK Pathway in the Rat Basolateral and Central Amygdala
TLDR
The observations suggest that the basolateral and central amygdala may be specifically involved in alcohol-seeking behavior induced by discrete cues, and c-Fos activation after reinstatement of ethanol seeking induced by discreet cues is compared with its putative partner and regulators. Expand
Time-dependent changes in alcohol-seeking behaviour during abstinence
TLDR
Alcohol-seeking behaviour may become more intense after long-term imposed abstinence and alcohol self-administration, extinction behaviour, and reinstatement of alcohol- seeking behaviour may be regulated by separate neural mechanisms. Expand
The effects of fatty acid amide hydrolase inhibitors on maintenance of cocaine and food self-administration and on reinstatement of cocaine-seeking and food-taking behavior in rats.
TLDR
The results indicate that FAAH inhibitors could be potent modulators of motivational and conditioned aspects of goal-directed behaviors with less prominent effects on consumatory behaviors. Expand
Different pattern of brain c-Fos expression following re-exposure to ethanol or sucrose self-administration environment
TLDR
The results suggest that at least some thalamo-cortical circuits become more responsive to ethanol-paired stimuli after prolonged abstinence and that ethanol- and sucrose-seeking behavior may be regulated by partially different neural mechanism(s). Expand
Baclofen attenuates cue-induced reinstatement of alcohol-seeking behavior in Sardinian alcohol-preferring (sP) rats.
TLDR
Results indicate that baclofen reduced cue-induced reinstatement of alcohol-seeking behavior in sP rats. Expand
Discriminative Stimulus Properties of Ethanol in the Rat: Differential Effects of Selective and Nonselective Benzodiazepine Receptor Agonists
TLDR
There are no major differences between full and partial, nonselective BZ receptor agonists in their ability to substitute for 1.0 g/kg dose of ethanol, and stimulation of BZ1 receptors alone is not sufficient to produce ethanol-like discriminative stimulus effects in the rat. Expand
Genetics of Lesch's typology of alcoholism
TLDR
The present results argue against any major role of the investigated polymorphisms in either Lesch type I or type II alcoholism. Expand
Extended blockade of the discriminative stimulus effects of nicotine with low doses of ethanol.
TLDR
The present results may indicate that the effects of ethanol on nicotine discrimination are not primarily related to blood ethanol levels, as well as suggesting inhibitory effects of nicotine on the rate of responding. Expand
BDNF rs 6265 polymorphism and COMT rs 4680 polymorphism in deficit schizophrenia in Polish sample.
TLDR
The analysis of the COMT rs4680 polymorphism in the present DS and NDS study shows that some genetic factors may be relevant in analyzing the reasons for the differentiation of schizophrenic subtypes. Expand
α-Synuclein expression in the brain and blood during abstinence from chronic alcohol drinking in mice
TLDR
The accumulation of alpha-synuclein in the amygdala, observed in this study, seems to be a common feature of alcohol and opiate abstinence, and may serve as a peripheral biomarker of chronic alcohol consumption. Expand
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