• Publications
  • Influence
Quantitative magnetic resonance imaging of brain development in premature and mature newborns
Definition in the living premature infant of the anatomical and temporal characteristics of development of critical brain structures is crucial for insight into the time of greatest vulnerability ofExpand
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  • Open Access
Cyclosporine neurotoxicity and its relationship to hypertensive encephalopathy: CT and MR findings in 16 cases.
OBJECTIVE The neurotoxic effects of cyclosporine therapy are well known but poorly understood. Imaging studies typically show subcortical edema predominantly affecting the posterior regions of theExpand
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Periventricular white matter injury in the premature infant is followed by reduced cerebral cortical gray matter volume at term
Periventricular white matter injury, that is, periventricular leukomalacia (PVL), the dominant form of brain injury in the premature infant, is the major neuropathological substrate associated withExpand
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  • Open Access
Neuroimaging advances in holoprosencephaly: Refining the spectrum of the midline malformation
  • J. Hahn, P. Barnes
  • Medicine
  • American journal of medical genetics. Part C…
  • 15 February 2010
Holoprosencephaly (HPE) is a complex congenital brain malformation characterized by failure of the forebrain to bifurcate into two hemispheres, a process normally completed by the fifth week ofExpand
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Developmental and Neurologic Status of Children after Heart Surgery with Hypothermic Circulatory Arrest or Low-Flow Cardiopulmonary Bypass
BACKGROUND: Deep hypothermia with either total circulatory arrest or low-flow cardiopulmonary bypass is used to support vital organs during heart surgery in infants. We compared the developmental andExpand
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Microstructural brain development after perinatal cerebral white matter injury assessed by diffusion tensor magnetic resonance imaging.
OBJECTIVE Brain injury in premature infants is characterized predominantly by perinatally acquired lesions in the cerebral white matter (WM). The impact of such injury on the subsequent developmentExpand
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Fetal central nervous system anomalies: MR imaging augments sonographic diagnosis.
PURPOSE To evaluate fetuses with sonographically suspected central nervous system anomalies to determine the frequency with which obstetric magnetic resonance (MR) imaging adds clinically usefulExpand
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Rickets vs. abuse: a national and international epidemic
In the May 2007 issue of Pediatric Radiology, the article “Can classic metaphyseal lesions follow uncomplicated caesarean section?” [1] suggested that enough trauma could occur under theseExpand
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Early detection of periventricular leukomalacia by diffusion-weighted magnetic resonance imaging techniques.
Periventricular leukomalacia (PVL), the principal form of brain injury in the premature infant, is characterized by overt focal necrotic lesions in periventricular white matter and less prominent,Expand
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Diffusion tensor brain imaging findings at term-equivalent age may predict neurologic abnormalities in low birth weight preterm infants.
BACKGROUND AND PURPOSE Low birth weight preterm infants are at high risk of brain injury, particularly injury to the white matter. Diffusion tensor imaging is thought to be more sensitive thanExpand
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  • Open Access