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Improving public health information: a data quality intervention in KwaZulu-Natal, South Africa.
- W. Mphatswe, K. Mate, +4 authors N. Rollins
- Bulletin of the World Health Organization
- 1 March 2012
OBJECTIVE To evaluate the effect of an intervention to improve the quality of data used to monitor the prevention of mother-to-child transmission (PMTCT) of the human immunodeficiency virus in South… Expand
Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice.
The amiloride-sensitive epithelial sodium channel, ENaC, is a heteromultimeric protein made up of three homologous subunits (alpha, beta and gamma) (1,2). In vitro, assembly and expression of… Expand
Decreased sodium ion absorption across nasal epithelium of very premature infants with respiratory distress syndrome.
OBJECTIVE AND STUDY DESIGN Successful adaptation to air breathing at birth depends on rapid absorption of fetal lung liquid that is mediated by activation of amiloride-sensitive sodium ion channels.… Expand
Improving a Mother to Child HIV Transmission Programme through Health System Redesign: Quality Improvement, Protocol Adjustment and Resource Addition
- Michele S Youngleson, Paul Nkurunziza, K. Jennings, J. Arendse, K. Mate, P. Barker
- PloS one
- 9 November 2010
Background Health systems that deliver prevention of mother to child transmission (PMTCT) services in low and middle income countries continue to underperform, resulting in thousands of unnecessary… Expand
A framework for scaling up health interventions: lessons from large-scale improvement initiatives in Africa
BackgroundScaling up complex health interventions to large populations is not a straightforward task. Without intentional, guided efforts to scale up, it can take many years for a new evidence-based… Expand
Sweat-testing in preterm and full-term infants less than 6 weeks of age.
Our objective was to examine the characteristics of preterm and full-term infants < or = 6 weeks old that influence the success of obtaining sufficient sweat for diagnosis of CF, and corresponding… Expand
Antiretroviral Drugs in the Cupboard are Not Enough: The Impact of Health Systems' Performance on Mother-to-Child Transmission of HIV
- P. Barker, W. Mphatswe, N. Rollins
- Journal of acquired immune deficiency syndromes
- 1 February 2011
Objective:To model the effect of health systems performance on rates of mother-to-child HIV transmission. Methods:We modeled the effect of variation in performance of the multiple steps of different… Expand
Pulmonary glucose transport in the fetal sheep.
- P. Barker, C. Boyd, C. Ramsden, L. Strang, D. Walters
- Chemistry, Medicine
- The Journal of physiology
- 1 February 1989
1. In the chronically catheterized sheep fetus between 122 and 143 days gestation the concentration of D-glucose in lung liquid was very low (usually less than 0.01 mM, the lower limit of detection… Expand
A mouse model for the renal salt-wasting syndrome pseudohypoaldosteronism.
- E. Hummler, P. Barker, +9 authors B. Rossier
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 14 October 1997
Aldosterone-dependent epithelial sodium transport in the distal nephron is mediated by the absorption of sodium through the highly selective, amiloride-sensitive epithelial sodium channel (ENaC) made… Expand
Macrolide antibiotics for cystic fibrosis.
BACKGROUND Cystic Fibrosis is characterised by chest infection, the antibiotic treatment of which has significantly improved the outlook for people with this condition. The unusual nature of… Expand