A mechanism-based classification of pain in multiple sclerosis
Nine types of MS-related pain are distinguished, which include trigeminal neuralgia and Lhermitte’s phenomenon, ongoing extremity pain, mixed pains secondary to lesions in the central motor pathways but mediated by muscle nociceptors, musculoskeletal pains, migraine, and treatment-induced pains.
BI 44370 TA, an oral CGRP antagonist for the treatment of acute migraine attacks: Results from a phase II study
Efficacy of BI 44370 TA was shown in a dose-dependent manner in the treatment of acute migraine attacks, and the frequency of adverse events was low in all groups.
Unilateral Cranial Autonomic Symptoms in Migraine
- P. Barbanti, G. Fabbrini, M. Pesare, N. Vanacore, R. Cerbo
- Medicine, PsychologyCephalalgia : an international journal of…
- 1 May 2002
The presence of UAs suggests an activation of the trigeminal-autonomic reflex, probably related to an over-activation of thetrigeminal afferent arm, in patients with migraine patients.
The phenotype of migraine with unilateral cranial autonomic symptoms documents increased peripheral and central trigeminal sensitization. A case series of 757 patients
- P. Barbanti, C. Aurilia, V. Dall’armi, G. Egeo, L. Fofi, S. Bonassi
- Medicine, PsychologyCephalalgia
- 8 February 2016
This study broadens the knowledge on the clinical and phenotypic characteristics of migraine with UAS, suggests pathophysiological implications, and supports the need for future prospective clinical studies.
Migraine and movement disorders
A critical appraisal of clinical and experimental data suggests that the extrapyramidal system is somehow related to migraine, and a more general role in the processing of nociceptive information and/or maybe part of the complex behavioral adaptive response that characterizes migraine may be suggested.
Donepezil in the treatment of hallucinations and delusions in Parkinson’s disease
- G. Fabbrini, P. Barbanti, C. Aurilia, C. Pauletti, G. Lenzi, G. Meco
- Medicine, PsychologyNeurological Sciences
- 1 April 2002
Donezepil was overall well tolerated, but a deterioration in motor disability was noted in 2 out of 8 patients, andHallucinations and delusions improved significantly in all patients.
Increased expression of dopamine receptors on lymphocytes in Parkinson's disease
The increased density of D1‐like and D2‐like receptors on PBL in de novo PD patients may represent an upregulation mechanism resulting from the diffuse impairment of the dopaminergic system in PD.
Amitriptyline Is Effective in Chronic But Not in Episodic Tension‐Type Headache: Pathogenetic Implications
Amitriptyline significantly reduced frequency and duration of headache as well as analgesic consumption in chronic, but not in episodic, tension‐type headache.
Excessive daytime sleepiness in de novo and treated Parkinson's disease
- G. Fabbrini, P. Barbanti, C. Aurilia, N. Vanacore, C. Pauletti, G. Meco
- Psychology, MedicineMovement disorders : official journal of the…
- 1 September 2002
Differences in ESS score variability were best explained by the treatment effect, whereas there was no clear correlation between PSQI and any of the clinical variables considered.
Dopamine hypersensitivity in migraine: role of the apomorphine test.
It is shown that migraineurs show a lower threshold for dopamine receptor activation than normal subjects, and symptoms due to postsynaptic dopamine receptors activation only appeared in migraineurs.