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Bielschowskysin, a gorgonian-derived biologically active diterpene with an unprecedented carbon skeleton.
Bielschowskysin was shown to exhibit antimalarial activity against Plasmodium falciparum as well as strong anticancer activity against two human cancer cell lines. Expand
New terpenoid constituents from Eunicea pinta.
The secondary metabolite composition of the gorgonian octocoral Eunicea pinta from San Andrés Island, Colombia, is described for the first time and the structures proposed earlier for several uprolide-type cembranolides need revision and that a minor stereochemical correction is also in order for succinolide. Expand
A crystallographically characterized nine-coordinate calcium-phosphocitrate complex as calcification inhibitor in vivo.
The preparation and crystal and molecular structure of a polymeric mixed salt of PC, namely [CaNa(PC)2(H2O)]n (CaNaPC), and its improved calcification inhibition properties compared to its precursor, NaPC are described. Expand
A novel series of vanadium-sulfite polyoxometalates: synthesis, structural, and physical studies.
Compound 3 comprises a rare example of a non-oxo vanadium(IV) species isolated from aqueous solution and in the presence of the reducing agent SO3(2-), while compound 4 represents a rare examples of an open-framework species isolated at room temperature (20 degrees C). Expand
New diterpenes of the pseudopterane class from two closely related Pseudopterogorgia species : isolation, structural elucidation, and biological evaluation
Abstract Parallel chemical investigations of the hexane and chloroform extracts of the sea plumes Pseudopterogorgia bipinnata and Pseudopterogorgia kallos has led to the discovery of seven newExpand
The spectroscopic and structural properties of copper(II) complexes of the novel tridentate (ONO) pyridine N-oxide ligand Hpoxap
Abstract A tridentate ligand (Hpoxap=2-(o-hydroxyphenyliminomethyl)pyridine N-oxide) has been synthesised by the Schiff condensation of 2-pyridinecarboxaldehyde N-oxide with 2-aminophenol. A seriesExpand
Antiplasmodial cembradiene diterpenoids from a Southwestern Caribbean gorgonian octocoral of the genus Eunicea
Abstract Five new representatives of the cembrane class of marine natural products have been isolated as minor metabolites from an undescribed species of Eunicea, a sea whip collected near theExpand
Preparation and structure of 2-(2-benzimidazol-2-yl)pyridine N-oxide and its complexes
Abstract The condensation product of pyridinecarboxaldehyde N-oxide with o-phenylenediamine yields a ligand 2-(2-benzimidazolyl)pyridine N-oxide (poxbim) which has been isolated in a free form. TheExpand
Synthesis and Structural Characterization of Trinuclear CuII−Pyrazolato Complexes Containing μ3-OH, μ3-O, and μ3-Cl Ligands. Magnetic Susceptibility Study of [PPN]2[(μ3-O)Cu3(μ-pz)3Cl3]
The nine-membered [−CuII−N−N−]3 ring of trimeric copper−pyrazolato complexes provides a sturdy framework on which water is twice deprotonated in consecutive steps, forming μ3-OH and μ3-O species. InExpand