P. Büscher

Publications254
h-index50
Citations8,584
Highly Influential Citations500
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Human African trypanosomiasis
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Options for Field Diagnosis of Human African Trypanosomiasis
TLDR
There is an urgent need for better tools for the field diagnosis of this neglected disease, and improved access to diagnosis and treatment for the population at risk remains the greatest challenge for the coming years.
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Treatment of human African trypanosomiasis--present situation and needs for research and development.
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Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration.
TLDR
A system for the real-time in vivo imaging of sequestration using transgenic luciferase-expressing parasites of the rodent malaria parasite Plasmodium berghei is reported, indicating a role for alternative parasite ligands and dissociating parasite sequestration from CM-associated pathology.
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International Study to Evaluate PCR Methods for Detection of Trypanosoma cruzi DNA in Blood Samples from Chagas Disease Patients
TLDR
This study represents a first crucial step towards international validation of PCR procedures for detection of T. cruzi in human blood samples by an external quality evaluation.
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The serum resistance-associated gene as a diagnostic tool for the detection of Trypanosoma brucei rhodesiense.
TLDR
Data strongly suggest that expression of the SRA gene is generally involved in resistance to lysis by NHS in T. b.
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Atypical Human Infections by Animal Trypanosomes
TLDR
Improvement, evaluation of new diagnostic tests, and field investigations are required for detection and confirmation of these atypical human trypanosomoses, which might be underestimated.
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Comparison of serological tests for Trypanosoma evansi natural infections in water buffaloes from north Vietnam.
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Towards a New Reference Test for Surra in Camels
TLDR
The ELISA/rISG75, having a performance comparable to that of the gold standard (the TL assay) and being independent of antigenic variation, may become a new reference test for surra in camels.
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Host-Parasite Interactions in Trypanosomiasis: on the Way to an Antidisease Strategy
African trypanosomiasis (AT) is a family of parasitic conditions affecting both humans and livestock, impairing development in sub-Saharan Africa, throughout the 10 million-km2 habitat zone of the…
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