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Sexual differences in onset of disease and response to exercise in a transgenic model of ALS
A possible neuroprotective effect of female sex hormones is suggested and the view that ALS patients should not avoid regular exercise is supported.
Chronic idiopathic polyneuropathy presenting in middle or old age: a clinical and electrophysiological study of 75 patients.
The clinical and electrophysiological features were prospectively studied of 75 patients (46 men and 29 women) with chronic polyneuropathy presenting in middle or old age in whom a diagnosis could
Power density and exposure time of He‐Ne laser irradiation are more important than total energy dose in photo‐biomodulation of human fibroblasts in vitro
From these experiments it is clear that exposure time and power density determine the effects of laser irradiation: both stimulation and inhibition of the observed cell properties can be obtained with the same laser on the same cells.
Chronic Mitochondrial Inhibition Induces Selective Motoneuron Death In Vitro: A New Model for Amyotrophic Lateral Sclerosis
An in vitro model of chronic motoneuron toxicity, based on malonate‐induced inhibition of complex II in the mitochondrial electron transport chain, shows that chronic mitochondrial inhibition leads to selective mot oneuron death, which is most likely apoptotic.
Dietary vitamin E levels affect outcome of permanent focal cerebral ischemia in rats.
After permanent focal cerebral ischemia, the infarct is larger in vitamin E-deficient rats than in rats raised on a diet with the usual, supraphysiological amount of vitamin E.
Quantitative EEG changes due to cerebral vasoconstriction. Indomethacin versus hyperventilation-induced reduction in cerebral blood flow in normal subjects.
Indomethacin andhyperventilation caused similar degrees of vasoconstriction; however, the increase in qEEG slow wave activity, which was observed only in the hyperventilation group, is apparently related to metabolic rather than haemodynamic factors.
Ovariectomy and 17β-estradiol modulate disease progression of a mouse model of ALS
It is concluded that treatment with E2 may also delay disease progression of post-menopausal women with ALS.
Anti-sulphatide antibodies in peripheral neuropathy.
Raised titres of anti-sulphatide antibodies occurred in several types of neuropathy, but all had some degree of sensory impairment and associated immunological abnormality.
Local application of collagen containing brain-derived neurotrophic factor decreases the loss of function after spinal cord injury in the adult rat
The results indicate that local application of BDNF results in a decreased loss of function in the partially transected rat spinal cord starting one day after injury.
CD81 and microglial activation in vitro: proliferation, phagocytosis and nitric oxide production
Data indicate that CD81 is involved in an important subset of microglial effector functions after CNS injury, and the functional effects of a CD81 antibody, AMP1, on cultured rat microglia are analysed.