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The Effect of Sericin from Various Extraction Methods on Cell Viability and Collagen Production
It is found that SS produced from various extraction methods has different molecular weights, zeta potential, particle size and amino acid content, and SS from all extraction methods could still promote collagen production in a concentration-dependent manner, even at high concentrations that are toxic to cells. Expand
Green synthesis of silk sericin-capped silver nanoparticles and their potent anti-bacterial activity
The Fourier transform infrared (FT-IR) spectroscopy result proved that the carboxylate groups obtained from alkaline degradation of SS would be a reducing agent for the generation of AgNPs while COO− and NH2 + groups stabilized the AgNBP and prevented their precipitation or aggregation. Expand
Potential applications of silk sericin, a natural protein from textile industry by-products
Fibroin has been used in textile manufacturing and for several biomaterial applications, whereas sericin is considered a waste material in the textile industry; however, after mixing with other polymers and cross-linking it can form a film or a scaffold with good characteristics that can be used in the cosmetic and pharmaceutical industries. Expand
Formulation and characterization of silk sericin-PVA scaffold crosslinked with genipin.
The results indicated that the composition of the scaffolds had a significant effect on their physical properties, and that can easily be tuned to obtain scaffolds suitable for biological applications. Expand
Properties and antityrosinase activity of sericin from various extraction methods
Pigments, primarily flavonoids and carotenoids from silk cocoons, were found to enhance tyrosinase inhibition of SS and urea extraction was the only method that provided clearly distinguishable bands and had the most significant impact on SS conformation. Expand
The effect of serum albumin on the aggregation state and toxicity of amphotericin B.
Serum albumin in blood attenuates the toxicity of amphotericin B at a membrane level by affecting its aggregation state, and may balance deleterious effects of AmB mediated by serum low-density lipoproteins. Expand
Monitoring of inflammatory mediators induced by silk sericin.
Sericin promotes the wound healing process without causing inflammation, and sericin-treated wounds were shown to heal faster and have lower levels of inflammatory mediators, as compared with the cream base-treated and normal saline-soaked wounds. Expand
The Effects of Sericin Cream on Wound Healing in Rats
Histological examination after 15 d of treatment with 8% sericin cream revealed complete healing, no ulceration, and an increase in collagen as compared to cream base-treated wounds, which showed some ulcersation and acute inflammatory exudative materials. Expand
Nanotechnology in drug delivery
Fundamentals of Nanotechnology in Drug Delivery.- Physicochemical Principles of Nanosized Drug Delivery Systems.- Block Copolymer Synthesis for Nanoscale Drug and Gene Delivery.- Supercritical FluidExpand
The Effect of Sericin with Variable Amino-Acid Content from Different Silk Strains on the Production of Collagen and Nitric Oxide
It is concluded that SS is not toxic to fibroblast cells, and methionine and cysteine content in SS are important factors to promote cell growth and collagen synthesis. Expand