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Pharmacokinetics, interactions with macromolecules and species differences in metabolism of DEHP.
The recent long-term carcinogenesis bioassay of di(2-ethylhexyl) phthalate (DEHP) in rats and mice reported by the National Toxicology Program was the first such bioassay to implicate DEHP as aExpand
Application of the thiobarbiturate assay to the measurement of lipid peroxidation products in microsomes.
By applying two different thiobarbiturate assay procedures in parallel to aliquots of a microsomal incubation mixture one can simultaneously monitor free malondialdehyde and malondialdehyde plusExpand
Toxic potential of the plasticizer Di(2-ethylhexyl) phthalate in the context of its disposition and metabolism in primates and man.
  • C. Peck, P. Albro
  • Biology, Medicine
  • Environmental health perspectives
  • 1 November 1982
Although human toxicity from exposure to the plasticizer di(2-ethylhexyl) phthalate (DEHP) is unknown, reports of animal toxicity from DEHP have stimulated extensive toxicological studies. In theExpand
Activation of nonspecific lipase (EC 3.1.1.-) by bile salts.
The enzyme nonspecific lipase (EC 3.1.1.-) from rat pancreas has been isolated and its amino acid composition determined. The amino acid composition confirms more indirect evidence that nonspecificExpand
Metabolism of diethylhexyl phthalate by rats. Isolation and characterization of the urinary metabolites.
Abstract The metabolites appearing in the urine of rats fed di(2-ethylhexyl)phthalate have been isolated by two procedures, thin-layer chromatography of the free metabolites, or thin-layer andExpand
The metabolism of 2-ethylhexanol in rats.
  • P. Albro
  • Chemistry, Medicine
  • Xenobiotica; the fate of foreign compounds in…
  • 1975
1. 2-Ethylhexanol was efficiently absorbed following oral administration to rats. 14C associated with 2-ethyl[1-14C]hexanol was rapidly excreted in respiratory CO2 (6-7%), faeces (8-9%) and urineExpand
Lipids of the earthworm Lumbricus terrestris.
The lipid composition of the earthworm Lumbricus terrestris has been reexamined under conditions intended to avoid enzymatic and chemical alterations during storage, extraction, and fractionationExpand
Identification of the metabolites of simple phthalate diesters in rat urine.
Abstract Rat urinary metabolites of orally-administered dimethyl, di- n -butyl and di- n -octyl phthalates have been isolated by high-pressure liquid chromatography on Porasil A. A linear gradient ofExpand
Absorption of aliphatic hydrocarbons by rats.
The percentage retention of aliphatic hydrocarbons from relatively simple mixtures administered intragastrically to rats is shown to be an inverse linear function of carbon number, at least for majorExpand