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Oxidative stress, aging, and diseases
Reactive oxygen and nitrogen species (RONS) are produced by several endogenous and exogenous processes, and their negative effects are neutralized by antioxidant defenses. Oxidative stress occursExpand
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  • Open Access
Quality of Life Determinants and Hearing Function in an Elderly Population: Osservatorio Geriatrico Campano Study Group
Background: Hearing impairment (HI) is a very common condition in elderly people and the epidemiology together with hearing-related problems is still poorly investigated. Moreover, the cognitiveExpand
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Congestive Heart Failure and Cognitive Impairment in an Older Population
OBJECTIVE: Congestive heart failure (CHF) is potentially preventable, and the identification of modifiable risk factors for cognitive impairment (CI) for older persons is a very important issue. WeExpand
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Angina-induced protection against myocardial infarction in adult and elderly patients: a loss of preconditioning mechanism in the aging heart?
OBJECTIVES The present study examined whether angina 48 h before myocardial infarction provides protection in adult and elderly patients. BACKGROUND The mortality rate for coronary artery diseaseExpand
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Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells
Apoptosis of arterial cells induced by oxidized low density lipoproteins (OxLDL) is thought to contribute to the progression of atherosclerosis. However, most data on apoptotic effects and mechanismsExpand
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Frailty predicts long‐term mortality in elderly subjects with chronic heart failure
Background  The elderly are characterized by a high prevalence of chronic heart failure (CHF) and frailty, which is a complex interaction of physical, psychological and social impairment. This studyExpand
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Role of clinical frailty on long-term mortality of elderly subjects with and without chronic obstructive pulmonary disease
Background and aims: Elderly subjects are characterized by a high prevalence of chronic obstructive pulmonary disease (COPD) and frailty. This study examined the predictive role of frailty onExpand
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Verbal Memory Impairment in Congestive Heart Failure
Cognitive dysfunction, mainly memory impairment, characterizes congestive heart failure (CHF). Aim of this study was to verify whether: (1) CHF has differential effects on primary and secondaryExpand
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Effects of melatonin in isolated rat papillary muscle
In conclusion, we found that melatonin possess anti‐adrenergic effect in isolated rat papillary muscle. This phenomenon was abolished in the presence of its receptor antagonist N‐acetyltryptamineExpand
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Role of metabolic therapy in cardiovascular disease
SummaryThe pathophysiological basis for the use of metabolic therapy in the treatment of heart failure is analyzed. Bioenergetical processes related to ATP bioavailability play a central role inExpand
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