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Repeat dosing of rocuronium 1.2 mg kg-1 after reversal of neuromuscular block by sugammadex 4.0 mg kg-1 in anaesthetized healthy volunteers: a modelling-based pilot study.
BACKGROUND Re-intubation and re-operation may occasionally be required after neuromuscular block (NMB) reversal. This study evaluated block onset times of a second dose of rocuronium (1.2 mg kg(-1))Expand
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M139 A POPULATION PHARMACOKINETIC‐PHARMACODYNAMIC ANALYSIS OF NOMEGESTROL ACETATE, OESTRADIOL AND OESTRONE AND THEIR RELATIONSHIP ON QTCF INTERVALS IN HEALTHY WOMEN RECEIVING MULTIPLE ORAL DOSES OF
M139 A POPULATION PHARMACOKINETIC-PHARMACODYNAMIC ANALYSIS OF NOMEGESTROL ACETATE, OESTRADIOL AND OESTRONE AND THEIR RELATIONSHIP ON QTCF INTERVALS IN HEALTHY WOMEN RECEIVING MULTIPLE ORAL DOSES OFExpand
M138 A RANDOMISED, DOUBLE‐BLIND, PLACEBO‐ AND POSITIVE‐CONTROLLED, PARALLEL‐GROUP TRIAL TO INVESTIGATE THE EFFECT OF MULTIPLE ORAL DOSES OF NOMAC/E2 ON QTCF INTERVALS IN HEALTHY WOMEN
associated with clinically relevant QTc interval prolongation in healthy women, even after dosing at five times the therapeutic dose. • NOMAC/E2 was well tolerated, both at the therapeutic dose andExpand