P Z Cassulis

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Immunoglobulin levels are elevated in the acquired immune deficiency syndrome (AIDS) and one class, IgA, has been suggested as a marker of disease progression. IgA is composed of two subclasses, IgA1 and IgA2; circulating IgA1 is roughly 85% of the total in healthy individuals. We have attempted to determine if the subclass distribution in the serum of AIDS(More)
We purified IgG by an automated chromatographic procedure, using a recombinant DNA-produced Protein G ligand bound to silica as the solid phase. The IgG can be separated from human serum in approximately 20 min with little operator manipulation. Recovery studies indicate that unconcentrated eluates contain 77-100% of the applied IgG. Concentration to(More)
skills, and results remain the same for two weeks after sampling. Furthermore, blood spotted on ifiter paper can be analyze We compared the sensitivity and specificity of these two methods, using 109 blood specimens that had been analyzed for lead and protoporphyrin. A true-positive result, a measure of the sensitivity, was defined as a protoporphyrin value(More)
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