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The interleukin-1 (IL-1) signalling pathway represents a paradigm for all IL-1 family cytokines (IL-1A, IL-1B, IL-18, IL-33, IL1F5 to IL1F10) as well as for the toll-like-receptor-induced pathways. Research on IL-1 signalling for more than 20 years has generated a large body of experimental data, which are scattered across many different publications. No(More)
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