P. Vaidyanathan

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Autoimmunity to insulin, glutamic acid decarboxylase and the tyrosine-phosphatase-like protein IA-2 is associated with type 1 diabetes. The production of self-molecules in thymus and secondary lymphoid tissues is critical for self-tolerance; reduced levels may impair tolerance and predispose to autoimmunity, as shown for insulin. Alternative splicing causes(More)
It has been believed for decades, that proteins are responsible for most of the genetically important functions in all cells. Due to this reason, most of the research in molecular biology was focused on identifying genes that encode proteins, and their roles in the genetic network. Recent studies indicate that noncoding RNAs play important roles in various(More)
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