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Although Montreal is in an endemic area, significant clinical histoplasmosis with systemic manifestations has been, until recently, infrequently diagnosed. However, since the autumn of 1963, 31 cases of clinically significant histoplasmosis have been seen by the authors. These were divided into two groups: (1) patients in whom the diagnosis was established(More)
Internal malignant tumours may stimulate the formation of tumour antigens which, by means of an antigen-antibody mechanism, can cause pruritus, ichthyosis, erythroderma, acanthosis nigricans, dermatomyositis, erythema-urticarial and vesiculo-bullous skin eruptions.Tumours may also interfere with normal immunity responses and allow various localized skin(More)
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