P. T. Doran

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The permanent ice covers of Antarctic lakes in the McMurdo Dry Valleys develop liquid water inclusions in response to solar heating of internal aeolian-derived sediments. The ice sediment particles serve as nutrient (inorganic and organic)-enriched microzones for the establishment of a physiologically and ecologically complex microbial consortium capable of(More)
The occurrence of groundwater in Antarctica, particularly in the ice-free regions and along the coastal margins is poorly understood. Here we use an airborne transient electromagnetic (AEM) sensor to produce extensive imagery of resistivity beneath Taylor Valley. Regional-scale zones of low subsurface resistivity were detected that are inconsistent with the(More)
There is growing evidence for ice and fluids near the surface of Mars with potential discharge of brines, which may preserve a record of past life on the planet. Proven techniques to sample Mars subsurface will be critical for future NASA astrobiology missions that will search for such records. The required technology studies are underway in the McMurdo Dry(More)
Given the high costs of conducting a drug-response trial, researchers are now aiming to use retrospective analyses to conduct genome-wide association studies (GWAS) to identify underlying genetic contributions to drug-response variation. To prevent confounding results from a GWAS to investigate drug response, it is necessary to account for concomitant(More)
Active retro-transposition by a synthetic L1 element in mice, Proc. Selective asymmetry in a conserved forebrain to midbrain projection, J. Exp. Zoolog. B. Mol. Dev. Neuropilin asymmetry mediates a left-right difference in habenular connectivity, Development 134, 857-865, 2007. A multi-step pathway for the establishment of sister chromatid cohesion, PLoS(More)
Thyroid hormone controls multiple independent programs required for limb development in Xenopus laevis metamorphosis, expression changes at metamorphosis induced by thyroid hormone in Xenopus laevis tadpoles, Dev. asymmetry of the zebrafish epithalamus guides dorsoventral innvervation of the midbrain target, Lateralization of the vertebrate brain: taking(More)
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