P Suryaprabha

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Several anti-cancer drugs are known to bring about their tumoricidal actions by a free radical dependent mechanism. Majority of the studies reported that adriamycin, mitomycin C, bleomycin, etc., augment free radical generation and lipid peroxidation process in vitro. Our results reported here suggest that following chemotherapy both stimulated and(More)
Serum IgG levels were significantly increased (P less than 0.001) in 33 (20 male and 13 female) essential hypertensive cases (mean = 2083.87 +/- 99.94 mg/dl) when compared to 30 (15 male and 15 female) random normotensive control subjects (mean = 993.84 +/- 72.25 mg/dl). Of the 33 cases, 12 (36.3%) were familial and the rest were sporadic. No significant(More)
Psoriasis is a common disorder characterized by marked increases in keratinocyte proliferation, abnormal patterns of keratinocyte differentiation, prominent alterations in dermal capillary vasculature and the presence of dermal and epidermal T cells, monocytes/macrophages and neutrophils. It is now known that psoriasis can occur due to abnormalities in(More)
We studied free radical generation, lipid peroxidation and the levels of essential fatty acids and of their metabolites in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Both superoxide and hydrogen peroxide generation by peripheral leukocytes but not malondialdehyde levels, as measured by thiobarbituric acid assay, were(More)
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