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Ambient levels of particulate matter have been linked to cardiovascular disease. The mechanisms mediating these associations are poorly understood. One candidate mechanism is inflammation. Using data from the Multi-Ethnic Study of Atherosclerosis (2000-2002), the authors investigated the relation between exposure to particulate matter of less than or equal(More)
Thorek's technique for reduction mammaplasty with free nipple graft, described in 1922, has progressively been superseded by procedures using a dermo-glandular pedicle. Following a description of the surgical procedure used, we present a series of 50 patients operated with an average follow-up of 14.6 months; the outcome of the nipple graft was particularly(More)
Facial nerve palsy disrupts both the static and dynamic equilibrium of the half-face involved. The imbalance worsens with age and senility further aggravates the situation. Palliative surgery can be used in complete intractable facial palsy or rarement for partial palsies or as a temporary treatment. The operation is proposed mostly for elderly patients and(More)
Infants born to human immunodeficiency virus type 1 (HIV-1)-infected mothers were immunized at birth and at ages 4, 12, and 20 weeks with low-, medium-, or high-dose recombinant gp120 vaccine with MF59 adjuvant (HIV-1(SF-2); n=52) or with MF59 alone as a placebo (n=9). An accelerated schedule (birth and ages 2, 8, and 20 weeks) was used for an additional 10(More)
OBJECTIVES The aim of this study was to determine whether oral zidovudine (ZDV) given during labour would provide a similar systemic exposure to the established intravenous regimen used to prevent mother-to-child transmission in HIV-infected pregnant women. METHODS ZDV pharmacokinetic parameters following oral administration during labour were determined(More)
The use of recombinant CD4-IgG2 in pediatric human immunodeficiency virus type 1 (HIV-1) infection was evaluated by single and multidose intravenous infusions in 18 children in a phase 1/2 study. The study drug was well tolerated, and dose proportionality was observed in terms of area under time-concentration curve and peak serum concentration. Acute(More)
INTRODUCTION Phalangeal neck fractures are unusual, occurring mainly in children. This study aims at assessing the results of treatment of this type of fracture and presents a new technique for displaced fractures namely intrafocal pinning. PATIENTS AND METHODS From January 2001 to January 2007, we treated 49 children (32 boys and 17 girls) with 52(More)
PURPOSE OF THE STUDY Fingertip crush injuries are frequent in young children. Rigorous care is required to avoid esthetic and functional sequelae, but treatment is often difficult. We report our experience focusing on simple therapeutic principles useful for everyday practice in the emergency room. MATERIAL AND METHODS We reviewed retrospectively 91(More)
PURPOSE OF THE STUDY Free iliac crest transfer as described by Taylor is an option for tibial bone reconstruction in traumatology. Our purpose was to evaluate results, bone reconstruction quality and delay for bone healing using microsurgical technique. MATERIAL 13 men were operated on between December 1986 and January 1994, mean aged 31 years (extreme(More)