P. S. Schomberg

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In ENU induced rat glioma model, the location of tumor is unpredictable and serial observation of neoplastic changes in a single lesion is not possible. We induced neoplastic transformation of cultured type-I astrocyte (AS-l) by exposure to ENU and observed the morphological changes of them. Since the importance of p53 alteration is stressed in human glial(More)
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