P. S. Kurjanov

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Apoprotein A-1 is the major protein of antiatherogenic high density lipoproteins and one of the key proteins regulating reverse cholesterol transport. The goal of this work was to study the association of the APOA1 gene polymorphism with development of atherosclerosis in the population of St. Petersburg. Allelic frequencies of polymorphic variants (−75)G/A(More)
The antiatherogenic role of high-density lipoproteins (HDL) was demonstrated by numerous experimental, clinical and epidemiological studies. The mechanism underlying the antiatherogenic potential of HDL is based on their involvement in reverse cholesterol transport (RCT) from peripheral tissues into the liver. Transmembrane transporter ABCG1 is a key RCT(More)
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