P. R. J. W. Ruding

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An endolymphatic hydrops was induced in the left ear of each of 32 guinea pigs by obliteration of the endolymphatic sac. Both the hydropic ear and the control ear were examined by electrocochleography 1,2, 4 or 8 months after obliteration of the sac using electrodes on the apex and near the round window. One month after obliteration, the threshold of the(More)
We investigated the histopathological changes of the guinea pig cochlea in experimentally induced endolymphatic hydrops 1, 2, 4 and 8 months after obliteration of the endolymphatic sac. In this paper special attention is given to the morphological changes created in Reissner's membrane. Reissner's membrane showed various foldings, bony wall connections,(More)
In this study scanning electron microscopy was used to examine the stereocilia and their cross-linkages in guinea pig cochleas 1, 2, 4 and 8 months after endolymphatic sac obliteration. Initial changes were restricted to the stereocilia of the outer hair cells and consisted of a disarrangement and bulging of the stereocilia with an interruption of their(More)
The relation between electrocochleographic and histological changes in experimental endolymphatic hydrops was studied 1, 2, 4, or 8 months after obliteration of the endolymphatic sac. An increase in the compound Action Potential (AP) threshold was found 2, 4, and 8 months after obliteration. This increase was strongly correlated with loss of outer hair(More)
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