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The paper analyses the problem of censored samples in experimental medicine. Some cases in such samples have indefinite digital values. Censoring may result from death of some animals in the test group of the disease studied. When the animals that survived in the test group are compared to the control group in which all the animals survived, the difference… (More)
This paper develops methodology for statistical analysis with censored and missing data in medical researches. The author gives the examples, in which the appearance of missing or censored cases is not random (nonignorable censoring mechanisms), and how to resolve the problem.
Catabolism of purine mononucleotides to hypoxanthine and xanthine in the liver is enhanced in rats resuscitated after a 6.5-min asphyxia. Reduced incorporation of14C-hypoxanthine into these nucleotides 30 min 1, and 3 days after resuscitation attests to its disturbed reutilization. This probably promotes activation of the xanthine oxidase reaction, leading… (More)