P. P. Medvedev

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The uses of the Genome Reference Consortium's human reference sequence can be roughly categorized into three related but distinct categories: as a representative species genome, as a coordinate system for identifying variants, and as an alignment reference for variation detection algorithms. However, the use of this reference sequence as simultaneously a(More)
Genomic sequence duplication is an important mechanism for genome evolution, often resulting in large sequence variations with implications for disease progression. Although paired-end sequencing technologies are commonly used for structural variation discovery, the discovery of novel duplicated sequences remains an unmet challenge. We analyze duplicons(More)
The GEOIK program was started in 1985 to obtain a system of fitted parameters of the Earth (EP–90) including fundamental geodetic constants, geocentric reference system, and the parameters of the figure and the gravitational field of the Earth. Initially, this Program caried out by the Topography Service of the Ministry of Defence of the Russian Federation(More)
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