P. P. Antony

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Apoptosis is a highly regulated process crucial for maintaining cellular homeostasis and development. The B-cell lymphoma 2 (Bcl-2) family of proteins play a crucial role in regulating apoptosis. Overexpressed Bcl-2 proteins are associated with the development and progression of several human cancers. Annona muricata is a tropical plant that belongs to the(More)
Gyroscopes are used in the navigation system of Launch Vehicles for estimating its instantaneous position on the trajectory path during flight. Similar low cost gyroscope devices can be used in sounding rockets also for estimating their spin rate, attitude etc. This paper explains the algorithm to extract angular rate over SPI interface from ADXRS450, which(More)
Polypharmacology, the discovery or design of drug molecules that can simultaneously interact with multiple targets, is gaining interest in contemporary drug discovery. Serine/threonine kinases are attractive targets for therapeutic intervention in oncology due to their role in cellular phosphorylation and altered expression in cancer. Quercetin, a naturally(More)
Hyperglycemia in diabetic patients results in a diverse range of complications such as diabetic retinopathy, neuropathy, nephropathy and cardiovascular diseases. The role of aldose reductase (AR), the key enzyme in the polyol pathway, in these complications is well established. Due to notable side-effects of several drugs, phytochemicals as an alternative(More)
Während unser Verständnis zur Genetik des Harnblasenkarzinoms im letzten Jahrzehnt kontinuierlich gewachsen ist, steckt die Untersuchung epigenetischer Phänomene bei dieser Erkrankungsgruppe noch in den Kinderschuhen. Zusehends in den Fokus der Forschung rückt aber die Analyse aberranter DNA-Methylierung, da in einer Reihe von Arbeiten ein direkter(More)
The enduring relationship between dietary patterns and human health has led us to investigate the bioactive components present in fruits and vegetables for a very long time. Berries, notably the popular ones such as strawberry, raspberry, blueberry, blackberry, and the Indian gooseberry, are among the best known dietary sources due to the presence of a wide(More)
Organic stilbazolium family single crystal 4-N, N-diethylamino-4-N-methyl-stilbazolium Iodide (DESI) has been successfully grown from aqueous methanol solution by adopting slow solvent evaporation technique. Single crystal X-ray diffraction analysis was carried out and it shows that DESI crystal belongs to triclinic structure with P-1 space group. The(More)
Phosphatidylinositols and their phosphorylated derivatives, phosphoinositides, play a central role in regulating diverse cellular functions. These phospholipids have been shown to interact with the hydrophobic TH domain of the tumor necrosis factor (TNF)-α-induced protein 8 (TIPE) family of proteins. However, the precise mechanism of interaction of these(More)
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