P Odada Sumba

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Seasonal epidemics of malaria occur in highland areas of western Kenya where transmission intensity varies according to rainfall. This study describes the seasonal changes in cytokine responses to Plasmodium falciparum liver-stage antigen 1 (LSA-1) by children (< or =17 years old) and adults (> or =18 years old) living in such a highland area. Fourteen- to(More)
The development of endemic Burkitt's lymphoma (eBL) is closely associated with Epstein-Barr virus (EBV) infection and holoendemic malaria infections. The role of EBV in the development of malignancy has been studied in depth, but there is still little known about the mechanisms by which malaria affects Burkitt's lymphomagenesis. Activation induced cytidine(More)
Background:Endemic Burkitt's lymphoma (eBL) has been associated with Epstein–Barr virus (EBV) and holoendemic Plasmodium falciparum malaria. But recent evidence suggests that other risk factors are involved.Methods:We hypothesised that selenoprotein glutathione peroxidase (GPx), a surrogate of nutritional status, is an important biomarker for eBL risk. We(More)
Background: The HIV/AIDS pandemic is one of the leading health challenges in the world and Kenya today. Kaposi’s sarcoma is the leading neoplasia in HIV/AIDS and is an AIDS defining illness. Human Herpesvirus 8 is the causative organism of this neoplasia. The interaction of HHV8 with HIV is critical in the development of the neoplasia and other HHV8(More)
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