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—In many communication situations, the transmitter and the receiver must be designed without a complete knowledge of the probability law governing the channel over which transmission takes place. Various models for such channels and their corresponding capacities are surveyed. Special emphasis is placed on the encoders and decoders which enable reliable(More)
Mutations in the p53 tumour-suppressor gene are among the most common genetic alterations in human cancers. In the present study we analysed the mutations in the p53 tumor-suppressor gene in 25 primary and 20 metastatic human prostate cancer specimens. DNA extracted from the paraffin-embedded sections was amplified by hot-start polymerase chain reaction,(More)
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