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One hundred and sixty-nine patients (aged 65-98 years) were randomised to receive either local or general anaesthesia for cataract surgery. Cognitive function was assessed using a battery of psychometric tests performed pre-operatively, and at 24 h, 2 weeks and 3 months postoperatively. Oxygen saturation, blood pressure and heart rate were monitored and the(More)
A pupillographic technique, an adaptation of the swinging light test, is described for the measurement of unilateral afferent pupillary defects. In normal persons it yielded accurate, reproducible estimates of the magnitude of artificial afferent defects made with neutral filters of 1 to 4 log units density. In 15 studies on 8 patients with unilateral optic(More)
Acycloguanosine (9-[-hydroxyethoxymethyl]guanine) (Wellcome 248U) has a highly specific and potent antiviral action against herpes-simplex virus (H.S.V.) types I and II in cell-culture systems and in animal models of H.S.V. infection in the brain, skin, and eye. Its efficacy in man was tested in twenty-four patients with dendritic corneal epithelial ulcers(More)
Sir, Fungal Keratitis Caused by Curvularia lunata, with Successful Medical Treatment Fungal keratitis is exacerbated by topical steroid use.1 We present a case of a non-resolving corneal ulcer, treated with topical antibiotics and betamethasone. The ulcer was found to be infected by Curvularia lunata. This has not previously been described in this country(More)
Seven Ridley Mark I anterior chamber lenses were removed from patients at St Thomas's Hospital. The lenses had been in place for an average of 15 years. The indication for removal was corneal endothelial decompensation with painful bullous keratopathy. Examination of the lenses under the scanning electron microscope showed remarkably similar morphology in(More)
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