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Polysomnograms were obtained from two groups of normal subjects (20 medical students and 20 elderly persons). The recordings included the usual sleep parameters (electroencephalograph, electrooculograph, and electromyograph of chin muscles) and respiratory data obtained by means of a pneumotachygraph (tidal volumes and respiratory frequency) and thoracic(More)
Development of durable plant genetic resistance to pathogens through strategies of QTL pyramiding and diversification requires in depth knowledge of polygenic resistance within the available germplasm. Polygenic partial resistance to Aphanomyces root rot, caused by Aphanomyces euteiches, one of the most damaging pathogens of pea worldwide, was previously(More)
The authors studied sleep organization and modifications in ventilation in 20 healthy subjects (11 men, 9 women) with an average age of 65 years. There was a diminution (in relation to young adults) in the quantity of sleep with a relative increase in light slow wave sleep and reduction in deep slow wave and REM sleep phases. A reduction was also noted in(More)
To assess the incidence of posthyperventilation apnea (PHA), breathing patterns after active voluntary hyperventilation were determined during EEG recording by means of: (1) a thermocouple in 1060 patients; (2) a pneumotachograph coupled with a capnograph in 100 further patients. All the patients were randomly chosen. PHA of 12.6 +/- 0.48 occurred in only(More)
Genome-wide association (GWA) mapping has recently emerged as a valuable approach for refining the genetic basis of polygenic resistance to plant diseases, which are increasingly used in integrated strategies for durable crop protection. Aphanomyces euteiches is a soil-borne pathogen of pea and other legumes worldwide, which causes yield-damaging root rot.(More)
BACKGROUND Stent thrombosis (ST) is a rare but serious complication following percutaneous coronary intervention. Analysis of thrombus composition from patients undergoing catheter thrombectomy may provide important insights into the pathological processes leading to thrombus formation. We performed a large-scale multicentre study to evaluate thrombus(More)
Dear Sir, Shape change is one of the earliest visible responses after platelet activation with a soluble agonist or following contact with an adhesive substratum (1). Platelet shape change is a composite of several distinct morphological changes. Early observations reported that ADP-activated platelets undergo transformation from a smooth discoid shape, to(More)
The effects of a single dose of 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a] [1,4]benzodiazepine (midazolam, Ro 21-3981, Dormicum), 15 mg, on both self-evaluated and all-night EEG-recorded sleep parameters were studied in 10 normal young volunteers. All self-evaluated parameters were modified under midazolam compared with placebo: the sleep onset(More)
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