P. M. Rasmussen

Learn More
Manipulations of the serotonin levels in the brain can affect impulsive behavior and influence our reactivity to conditioned reinforcers. Eating, tobacco smoking, and alcohol consumption are reinforcers that are influenced by serotonergic neurotransmission; serotonergic hypofunction leads to increased food and alcohol intake, and conversely, stimulation of(More)
a Neurobiology Research Unit, University Hospital Rigshospitalet, Copenhagen, Denmark b Center for Integrated Molecular Brain Imaging, Copenhagen, Denmark c Danish Center for Magnetic Resonance Imaging, Hvidovre University Hospital, Denmark d Department of Biostatistics, University of Copenhagen, Denmark e DTU Informatics, Technical University of Denmark,(More)
CONTEXT Both hallucinogens and 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") have direct agonistic effects on postsynaptic serotonin(2A) receptors, the key site for hallucinogenic actions. In addition, MDMA is a potent releaser and reuptake inhibitor of presynaptic serotonin. OBJECTIVE To assess the differential effects of MDMA and hallucinogen(More)
UNLABELLED Stress sensitivity and serotonergic neurotransmission interact, e.g. individuals carrying the low-expressing variants (S and LG) of the 5-HTTLPR promoter polymorphism of the serotonin transporter (SERT) gene are at higher risk for developing mood disorders when exposed to severe stress and display higher cortisol responses when exposed to(More)
The neurobiology underlying obesity is not fully understood. The neurotransmitter serotonin (5-HT) is established as a satiety-generating signal, but its rewarding role in feeding is less well elucidated. From animal experiments there is now evidence that the 5-HT(4) receptor (5-HT(4)R) is involved in food intake, and that pharmacological or genetic(More)
Brain imaging in Klinefelter syndrome (47, XXY) (KS), a genetic disorder characterized by the presence of an extra X chromosome, may contribute to understanding the relationship between gene expression, brain structure, and subsequent cognitive disabilities and psychiatric disorders. We conducted the largest to date voxel-based morphometry study of 65 KS(More)
Department of Endocrinology and Internal Medicine (MEA), Aarhus University Hospital, 8000 Aarhus C, Denmark Department of Molecular Medicine, Aarhus University Hospital, 8200 Aarhus N, Denmark Center of Functionally Integrative Neuroscience, Aarhus University Hospital, 8000 Aarhus C, Denmark Department of Clinical Genetics, Vejle Hospital, Sygehus(More)
  • 1