P. M. Rasmussen

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CONTEXT Both hallucinogens and 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") have direct agonistic effects on postsynaptic serotonin(2A) receptors, the key site for hallucinogenic actions. In addition, MDMA is a potent releaser and reuptake inhibitor of presynaptic serotonin. OBJECTIVE To assess the differential effects of MDMA and hallucinogen(More)
UNLABELLED Stress sensitivity and serotonergic neurotransmission interact, e.g. individuals carrying the low-expressing variants (S and LG) of the 5-HTTLPR promoter polymorphism of the serotonin transporter (SERT) gene are at higher risk for developing mood disorders when exposed to severe stress and display higher cortisol responses when exposed to(More)
Manipulations of the serotonin levels in the brain can affect impulsive behavior and influence our reactivity to conditioned reinforcers. Eating, tobacco smoking, and alcohol consumption are reinforcers that are influenced by serotonergic neurotransmission; serotonergic hypofunction leads to increased food and alcohol intake, and conversely, stimulation of(More)
The neurobiology underlying obesity is not fully understood. The neurotransmitter serotonin (5-HT) is established as a satiety-generating signal, but its rewarding role in feeding is less well elucidated. From animal experiments there is now evidence that the 5-HT(4) receptor (5-HT(4)R) is involved in food intake, and that pharmacological or genetic(More)
In the paper entitled " Neuroanatomical correlates of Klinefelter syndrome studied in relation to the neuropsychological profile " 1–9 we have become aware, that the reported p-value for the comparison of Klinefelter Syndrome participants and control participants on the Stroop Color Word Test variable " SCWT diff " in Table 2 is incorrect. The correct value(More)
Capillary flow patterns are highly heterogeneous in the resting brain. During hyperemia, capillary transit-time heterogeneity (CTH) decreases, in proportion to blood's mean transit time (MTT) in passive, compliant microvascular networks. Previously, we found that functional activation reduces the CTH:MTT ratio, suggesting that additional homogenization(More)
Does harm avoidance mediate effects of recollected parental bonding on mental distress in adulthood? Comprehensive Psychiatry, pages –, 2014. In press. The heritability of prostate cancer in the nordic twin study of cancer. and Gitte Moos Knudsen. In abstinent MDMA-users the cortisol awakening response is offset but associated with prefrontal serotonin(More)
Brain imaging in Klinefelter syndrome (47, XXY) (KS), a genetic disorder characterized by the presence of an extra X chromosome, may contribute to understanding the relationship between gene expression, brain structure, and subsequent cognitive disabilities and psychiatric disorders. We conducted the largest to date voxel-based morphometry study of 65 KS(More)
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