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Interpretation of magnetic resonance angiography (MRA) is problematic due to complexities of vascular shape and to artifacts such as the partial volume effect. The authors present new methods to assist in the interpretation of MRA. These include methods for detection of vessel paths and for determination of branching patterns of vascular trees. They are(More)
Multi-probe dynamic biomedical imaging promises powerful tools for the visualization and elucidation of complex biological processes. Recent research aims to simultaneously dissect the spatial-temporal distributions of source signals that often represent a composite of multiple biomarkers independent of spatial resolution. We report a hybrid unmixing method(More)
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) can characterize vascular heterogeneity, and has potential utility in assessment of the efficacy of angiogenesis inhibitors in cancer treatment. Due to the heterogeneous nature of tumor microvasculature, the measured signals can be represented as the mixture of the permeability images(More)
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