P . Koshy Mathews

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The bone diagnostic instrument (BDI) is being developed with the long-term goal of providing a way for researchers and clinicians to measure bone material properties of human bone in vivo. Such measurements could contribute to the overall assessment of bone fragility in the future. Here, we describe an improved BDI, the Osteoprobe IItrade mark. In the(More)
Here we describe modifications that allow the bone diagnostic instrument (BDI) [P. Hansma et al., Rev. Sci. Instrum. 79, 064303 (2008); Rev. Sci. Instrum. 77, 075105 (2006)], developed to test human bone, to test the femora of mice. These modifications include reducing the effective weight of the instrument on the bone, designing and fabricating new probe(More)
A performance analysis on a vapour compression refrigeration system with various refrigerants mixture of R152a, RE170, R600a, and R290 were done for various mixture ratios and their results were compared with R134a as possible alternative replacement. The results showed that all of the alternative refrigerants investigated in the analysis except R431A, [R(More)
Tissue mechanical properties reflect extracellular matrix composition and organization, and as such, their changes can be a signature of disease. Examples of such diseases include intervertebral disk degeneration, cancer, atherosclerosis, osteoarthritis, osteoporosis, and tooth decay. Here we introduce the tissue diagnostic instrument (TDI), a device(More)
An understanding of the mechanical behavior of polymers is critical towards the design, implementation, and quality control of such materials. Yet experiments and method for the characterization of material properties of polymers remain challenging due the need to reconcile constitutive assumptions with experimental conditions. Well-established modes of(More)
A performance analysis on a vapour compression refrigeration system with various eco-friendly refrigerants of HFC152a, HFC32, HC290, HC1270, HC600a and RE170 were done and their results were compared with R134a as possible alternative replacement. The results showed that the alternative refrigerants investigated in the analysis RE170, R152a and R600a have a(More)
This paper presents the analysis results of R429A, R430A, R431A and R435A as drop in substitute for R152a at various evaporating temperature with condenser temperature 30°C, 40°C and 50°C. A theoretical study of thermodynamic properties such as pressure, density, and specific volume, latent heat of vaporization compression index, and critical values are(More)
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