P. J. van Houdt

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Efficacy of radiotherapy treatment depends on the specific characteristics of tumorous tissues. For the determination of these characteristics, clinical practice uses Dynamic Contrast Enhanced (DCE) Magnetic Resonance Imaging (MRI). DCE-MRI data is acquired and modeled using pharmacokinetic modeling, to derive per voxel a set of parameters, indicative of(More)
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) provides quantitative metrics (e.g. Ktrans, ve) via pharmacokinetic models. We tested inter-algorithm variability in these quantitative metrics with 11 published DCE-MRI algorithms, all implementing Tofts-Kermode or extended Tofts pharmacokinetic models. Digital reference objects (DROs) with(More)
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