Learn More
The enzymatic hydroxylation of 3,4-benzpyrene was not detected in human placentas obtained after childbirth from nonsmokers, whereas this enzyme activity was present in placentas obtained from individuals who smoked cigarettes. The degree of induction of benzpyrene hydroxylase caused by cigarette smoking varied in different individuals. Treatment of(More)
This study was designed to assess the use of pulse oximetry (PO) to determine the adequacy of radial and ulnar arterial blood flow by comparing measurements of digital arterial hemoglobin oxygen saturation (SaO2) with conventional visual determination of palmar flush (PF) using a simple occlusion test (SOT) or the Allen's test (AT) in 48 healthy volunteers.(More)
The in vitro hydroxylation of zoxazolamine was compared with the hydroxylation of benzo[a]pyrene (BP) in full-term placentas from 11 nonsmokers and from 13 women who smoked cigarettes during pregnancy. Cigarette smoking increased the average zoxazolamine and benzo[a]pyrene hydroxylase activities 13- and 39-fold, respectively. A 59-fold range in(More)
Addition of 10(-4) M 7,8-benzoflavone to homogenates of human liver samples obtained by autopsy or surgical biopsy increased the rate of benzo[a]pyrene hydroxylation up to 11-fold. 7,8-Benzoflavone also increased the rates of hydroxylation of zoxazolamine and antipyrine at 10(-4) M but inhibited these reactions at 10(-6) M. The effects of 7,8-benzoflavone(More)
Manual recording of physiological data in patients receiving anesthesia or intensive care infrequently meets medical requirements or legal documentation standards. Automated recording allows the generation of reliable data that can be integrated into the patient's medical record. Such a system is beginning to function at University Hospital at Stony Brook,(More)
The alpha-adrenergic agonist oxymetazoline was compared to cocaine and to lidocaine with epinephrine with respect to prevention of epistaxis on nasotracheal intubation. The nares of three groups of 14 patients each were topically pretreated with 4% lidocaine with 1:100,000 epinephrine (group 1), 10% cocaine (group 2), or 0.05% oxymetazoline (group 3) prior(More)