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A discontinuous Galerkin method for approximating the Vlasov-Poisson system of equations describing the time evolution of a collisionless plasma is proposed. The method is mass conservative and, in the case that piecewise constant functions are used as a basis, the method preserves the positivity of the electron distribution function. The performance of the(More)
Traditional numerical discretizations of conservative systems generically yield an artiicial secular drift of any nonlinear invariants. In this work we present an explicit nontraditional algorithm that exactly conserves these invariants. We illustrate the general method by applying it to the three-wave truncation of the Euler equations, the Lotka{Volterra(More)
  • D. Stoppa-Lyonnet, M. Caligo, D. Eccles, D. G. R. Evans, N. E. Haites, N. S. Hodgson +5 others
  • 1999
The usefulness of genetic testing for risk assessment relies on three parameters: the probability that a given phenotype reflects a genetic trait, the genetic heterogeneity, and the allelic heterogeneity. Concerning breast cancer genetic testing, all these parameters preclude easy genetic diagnosis of a woman with a breast cancer family history and require(More)
In the United Kingdom, concerns about the consequences of genetic testing and the eligibility for life assurance have worried families wanting to pursue genetic testing for later onset disorders such as familial cancers and neurological disease. The recent history and development of the insurance and genetic testing guidelines in the UK is interesting and(More)
The multiple endocrine neoplasia type 2A syndrome (MEN 2A), comprising medullary thyroid carcinoma (MTC), phaeochromocytoma and primary hyperparathyroidism, is inherited in autosomal dominant fashion on chromosome 10. The specific genetic abnormality was initially localised to a site close to the centromere of chromosome 101,2 and, more recently, has been(More)