P . J . Delwaide

Learn More
Motor cortex excitability was studied by transcranial magnetic stimulation (TMS) in 17 patients with Alzheimer's disease (AD). Resting and active thresholds for TMS were significantly reduced in AD patients compared to young and aged healthy subjects. The maximum amplitude of the motor response evoked by TMS was also significantly increased in AD patients.(More)
BACKGROUND AND PURPOSE Prevalence and characteristics of ipsilateral upper limb motor-evoked potentials (MEPs) elicited by focal transcranial magnetic stimulation (TMS) were compared in healthy subjects and patients with acute stroke. METHODS Sixteen healthy subjects and 25 patients with acute stroke underwent focal TMS at maximum stimulator output over(More)
We have studied habituation of the pattern-reversal visual evoked potential (VEP) in healthy volunteers (n = 16) and in patients suffering from migraine without (n = 27) or with aura (n = 9). Five blocks of 50 responses at a stimulation rate of 3.1 Hz were sequentially averaged and analyzed separately for latencies, peak-to-peak amplitudes of N1-P1 and(More)
The facilitation of the tendon reflex of quadriceps, induced by voluntary contraction of a muscle group in the upper limb, evolves in the three phases and depends on several factos. These include the strength and type (ballistic or ramp) of the contraction. In the absence of any electromyographic activity in the conditioning muscle (from a lesion of its(More)
Modification of soleus and anterior tibial anterior horn cell excitability following ipsilateral and contralateral stimulations of the sural nerve was studied by either the H reflex (for the soleus and anterior tibial muscles) or the F response (for the anterior tibial muscles). Several intensities of stimulation were employed. In every instance the(More)
Functional changes in the organisation of neuronal circuitries are generally used to explain parkinsonian motor symptoms and levodopa-induced dyskinesias. Based on information from histology and neurophysiological microrecordings of specific basal ganglia nuclei, the most widely accepted scheme is based on a central loop which starts in the cerebral cortex,(More)
In order to determine the mono- or oligosynaptic character of connections between pyramidal axons and individual spinal motor neurons, we constructed peri-stimulus time histograms (PSTHs) of the firing probability of voluntarily activated single motor units (SMUs) of various upper and lower limb muscles upon slightly suprathreshold transcranial anodal(More)
BACKGROUND AND PURPOSE Transcranial magnetic stimulation (TMS) has been proposed as a prognostic tool in stroke patients. Most of the previous studies agree in considering the presence of motor-evoked potentials (MEPs) in the first days after a stroke as an indicator of good outcome. In the present study, we have assessed the prognostic value of the absence(More)
This study compares the facilitation of various lower limb reflex arcs brought about by a selective contraction of a well-defined upper limb muscle group in able-bodied healthy subjects. Quantitatively (results expressed as a percentage of maximal motor response), the quadriceps tendon reflex is facilitated more than the soleus and biceps femoris tendon(More)