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Both genes encoding U3 small nuclear RNA (snRNA) from the budding yeast Saccharomyces cerevisiae were recently shown to be interrupted by introns of the type removed by the pre-mRNA splicing machinery. We previously described one of the two U3 genes from the fission yeast Schizosaccharomyces pombe. In the present work, the second S. pombe U3 coding sequence(More)
Signal recognition particle (SRP) is a ribonucleoprotein required for targeting of presecretory proteins to the endoplasmic reticulum (reviewed in 1). The well-studied canine particle is composed of six polypeptides and one RNA molecule often referred to as 7SL. We report here the sequence and proposed structure of an SRP RNA homolog from Tetrahymena,(More)
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