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Previous studies have suggested that the apparent dissociation constant of blood carbonic acid (pK') may actually vary in acutely ill patients. We prospectively compared the pK' of healthy control subjects to that of patients undergoing cardiopulmonary resuscitation (CPR). Arterial blood obtained from 20 patients undergoing CPR and from 30 healthy(More)
The Henderson-Hasselbalch equation is commonly used to calculate plasma bicarbonate and CO2 content (tCO2) from blood gas measurements and an assumed constant value of the apparent dissociation constant of blood carbonic acid (pK'). Several studies have reported pK' to be variable in critically ill patients. We prospectively compared the pK' of patients in(More)
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