Learn More
In order to try to determine whether differentiated olfactory receptors turn over (die and are replaced by newly differentiated cells) during adult life, mice were injected with a single dose of 3H-thymidine at either 2 or 4 months of age and allowed to survive for up to 12 months; they were caged in a laminar flow unit to prevent rhinitis. Counts of(More)
A quantitative study of synapse formation in the mouse olfactory bulb has been carried out using serial sections. Volumetric synaptic density as well as absolute number of synapses per olfactory bulb for eight distinct synaptic types have been determined at 15 different ages, from the beginning of synapse formation at embryonic day 14 (E14) to postnatal day(More)
Serial thin sections of the mouse olfactory bulb from the fourteenth day of gestation (E14) to postnatal to 44 (P44) have been examined in order to study morphogenesis of individual synaptic junctions. At the initiation of synapse formation structures are found that resemble postsynaptic densities but are facing extracellular space or unmodified processes.(More)
The early differentiation of photoreceptors and horizontal cells in the mouse retina has been studied with serial thin sections and reconstructions in embryos on the fifteenth and seventeenth days of gestation (E15 and E17). The following developmental sequences have been inferred. At E15 photoreceptors develop from ventricular cells when a long vitreal(More)
Developing amacrine and ganglion cells have been graphically reconstructed from a series of 567 consecutive thin sections of the E17 mouse retina on the first day when an obvious inner plexiform layer (IPL) is present and 2 days later than for our previous study of amacrine cell formation at E15 (Hinds and Hinds ('78). At E17 amacrine cells of the(More)
A study comparing perceptual judgments of vowels produced by deaf children taught to speak by using a computer-based aid (experimental group, E) and by conventional techniques (control group, C) revealed feedback-related differences. These concerned the ability to reorganise articulatory performance, intelligibility of vowels after training, and the(More)
This study examined the perceived changes in vowel articulation by profoundly deaf children as a function of the method of teaching: with visual feedback provided by the Computer Vowel Trainer (CVT) vs conventional methods. The assessment carried out by experienced listeners consisted in marking the sounds heard on the vowel quadrilateral. It was found that(More)
The ability of severely deaf school children to master fricative production and the fricative-affricate distinction was studied over a period of 6 months. The children were given daily speech therapy and half of them received, in addition, visual feedback from a microprocessor-based speech training aid - the 'Fricative and Timing Aid'. The speech of a third(More)
The ability of profoundly deaf schoolchildren to learn the voicing distinction was studied over a period of 6 months. The children were given daily speech therapy and half of them received, in addition, visual feedback from a microprocessor-based speech training aid - the Fricative and Timing Aid. Their performance was analysed in terms of the acquisition(More)