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Despite 50 years of pharmacological and psychosocial interventions, schizophrenia remains one of the leading causes of disability. Schizophrenia is also a life-shortening illness, caused mainly by poor physical health and its complications. The end result is a considerably reduced lifespan that is marred by reduced levels of independence, with few novel(More)
Background: Treatment-resistant depression (TRD) is a significant mental health problem leading to substantial morbidity and mortality. Despite the disability associated with this condition, there is little information available about the determinants of this disability, and essentially no information available about the cognitive impairments seen in TRD.(More)
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