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Cerebrospinal fluid (CSF) and serum levels of interleukin-2 (IL-2), soluble IL-2 receptors (sIL-2R), neopterin,l-tryptophan (l-TRP) and β2-microglobulin ((β2-M) were measured in 31 untreated multiple sclerosis patients in acute exacerbation and 27 normal controls. Twenty-six patients showed the relapsing-remitting type of disease (RRMS); 5 had a(More)
OBJECTIVE We conducted a single-centre, randomised, double-blinded, placebo-controlled phase II clinical study to test safety and efficacy of a 12-week therapy with low-dose (700 mg/daily) or high-dose (2800 mg/daily) of NAC. METHODS Twenty-one patients (DeltaF508 homo/heterozygous, FEV1>40% pred.) were included in the study. After a 3-weeks placebo(More)
In five children and one adolescent biopsies of the septal cartilage partially covered with inner perichondrium, were removed during septoplasty and buried into the retroauricular region for 1.8 to 5.3 years. After removal the implants were equal or reduced size. Histologically the cartilage showed its original structure in three children who were before(More)
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