Learn More
Unfixed metaphase chromosome preparations from human lymphocyte cultures were immunofluorescently labelled using antibodies to defined histone epitopes. Both mouse monoclonal antibody HBC-7, raised against the N-terminal region of H2B, and rabbit serum R5/12, which recognizes H4 acetylated at Lys-12, gave non-uniform labelling patterns, whereas control(More)
In Ch], Cheeger proved the following general lower bound for the rst eigenvalue 1 of a closed Riemannian manifold: Theorem ((Ch]): 1 1 4 h 2 ; where h = inf N area(N) min(vol(A); vol(B)) where N runs over (possibly disconnected) hypersurfaces of M which divide M into two pieces A and B, and where area denotes (n ? 1)-dimensional volume, and vol denotes(More)
We investigate the relation between the Korteweg-de Vries and modified Korteweg-de Vries equations (KdV and mKdV), and find a new algebro-analytic mechanism, similar to the Lax L-A pair, which involves a family of first-order operators Q λ depending on a spectral parameter λ, instead of the third-order operator A. In our framework, any generalized(More)
The human lens is comprised largely of crystallin proteins assembled into a highly ordered, interactive macro-structure essential for lens transparency and refractive index. Any disruption of intra- or inter-protein interactions will alter this delicate structure, exposing hydrophobic surfaces, with consequent protein aggregation and cataract formation.(More)
We consider the problem of enumerating permutations in the symmetric group on n elements which avoid a given set of consecutive pattern S, and in particular computing asymptotics as n tends to infinity. We develop a general method which solves this enumeration problem using the spectral theory of integral operators on L 2 ([0, 1] m), where the patterns in S(More)
The cellular response, in terms of cell cycle arrest(s) and apoptosis, to radiation-induced DNA damage was studied. Experiments were performed on both mitogen-stimulated and resting peripheral blood lymphocytes (PBLs) from normal and cancer-prone (C-P) individuals. The C-P individuals comprised three patients carrying germline p53 mutations and three(More)