• Publications
  • Influence
A KEY ROLE FOR OREXIN IN PANIC ANXIETY
Panic disorder is a severe anxiety disorder with recurrent, debilitating panic attacks. In individuals with panic disorder there is evidence of decreased central γ-aminobutyric acid (GABA) activityExpand
  • 282
  • 17
Changes in the carboxyl-terminal repeat region affect extracellular activity and glucan products of Streptococcus gordonii glucosyltransferase.
Glucans produced by the glucosyltransferase (GTF) of Streptococcus gordonii confer a hard, cohesive phenotype (Spp+) on colonies grown on sucrose agar plates. S. gordonii strains with specificExpand
  • 46
  • 4
  • PDF
Genetic Analysis of the rgg-gtfG Junctional Region and Its Role in Streptococcus gordonii Glucosyltransferase Activity
ABSTRACT Glucans synthesized by glucosyltransferase enzymes of oral streptococci facilitate bacterial accumulation on surfaces. The Streptococcus gordonii glucosyltransferase gene, gtfG, isExpand
  • 18
  • 1
  • PDF
Characterization of the Streptococcus gordonii chromosomal region immediately downstream of the glucosyltransferase gene.
The Streptococcus gordonii glucosyltransferase gene, gtfG, is positively regulated by the upstream determinant rgg. In the present study, two ORFs, transcribed on the opposite DNA strand, wereExpand
  • 13
  • PDF
Initial characterization of the Streptococcus gordonii htpX gene.
Examination of the Streptococcus gordonii chromosomal region, which lies immediately upstream of the glucosyltransferase positive regulatory determinant rgg, revealed two open reading frames. BasedExpand
  • 13