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Patients were treated with pulse CTX (15 mg/kg with dose titrated to renal function) and steroids (pulse methylprednisolone 1 g/day for 3 days followed by oral prednisolone 1 mg/kg for a period of 6 weeks and tapered to stop). In patients who progressed to ESKD within 3 months, further pulses of CTX were withheld. The study included 16 males and 2 female.(More)
A 25-year-old female presented with decreased urine output, deranged renal function, thrombocytopenia, and hemolytic anemia. Kidney biopsy was consistent with thrombotic microangiopathy with acute cortical necrosis and Immunoglobulin A nephropathy (IgAN). Hemolytic anemia, thrombocytopenia and urine output improved after five sessions of plasma exchange.(More)
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