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There is growing evidence that atypical antipsychotics may be effective in the treatment of acute bipolar depression. Results from randomized, placebo-controlled trials support the use of quetiapine monotherapy and a combination of olanzapine-fluoxetine in the depressed phase of bipolar disorder, while only limited data exists regarding the use of(More)
If treatments for cognitive impairment are to be utilized successfully, clinicians must be able to determine whether they are effective and which patients should receive them. In order to develop consensus on these issues, the International Society for CNS Clinical Trials and Methodology (ISCTM) held a meeting of experts on March 20, 2014, in Washington,(More)
MAVEN (Management and Authenticity Verification of multimedia contENts) is a European FP7 Project focused on the development of a suite of tools for multimedia data management and security. MAVEN objectives are centered on two key concepts, search and verify, integrated in a coherent manner: the system first searches for digital contents containing objects(More)
In medically complex patients with multiple comorbid illnesses who require concomitant medications, selecting the optimal antidepressant (ie, low risk of adverse effects and/or pharmacokinetic interactions) for an individual patient is critical for positive long-term patient outcomes. The serotonin-norepinephrine reuptake inhibitors (SNRls) are increasingly(More)
INTRODUCTION Bipolar disorder is frequently associated with obsessional symptoms. However, no reports have identified a pattern of obsessionality that is associated with a specific mood stabilizer treatment. METHODS A chart review was conducted on five patients with bipolar II disorder who spontaneously reported a form of obsessionality characterized by(More)
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