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A formalism is introduced to represent the connective organization of an evolving neuronal network and the effects of environment on this organization by stabilization or degeneration of labile synapses associated with functioning. Learning, or the acquisition of an associative property, is related to a characteristic variability of the connective… (More)
A biochemical mechanism, expressed as a system of diffusion equations with non linear coupling on the muscle membrane, quantitatively accounts for the development of the neuromuscular junction and for the epigenetic dependence on the afferent multimessages of the focal and distributed synaptic topologies.