P Comfurius

Learn More
The binding of affinity-purified anticardiolipin antibodies (ACA) to liposomes that contained cardiolipin or phosphatidylserine was investigated. ACA bound to these liposomes only in the presence of plasma or serum, which indicated a requirement for a plasma component. This component--referred to as aca-cofactor--was purified; its activity to support ACA(More)
A modification of the phospholipase D-catalyzed synthesis of phosphatidylserine is described, which allows the handling of small quantities of lipid without the need for an ether-water system. By using octylglucoside to disperse the lipid during the enzymatic conversion, it was possible to reduce the volume of the reaction mixture to 50-100 microliters. The(More)
  • 1