P C Rubin

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Three cases of cortical blindness complicating eclampsia are described, with magnetic resonance imaging (MRI) and X-ray computed tomography (CT). The correspondence of MRI lesions (hyperintense on T2 weighted, and hypointense on T1 weighted sections) and low attenuation lesions on CT scan indicated ischaemia rather than haemorrhage as the pathological(More)
Atenolol was compared with placebo in a randomised and double-blind prospective study of 120 women with mild to moderate pregnancy-associated hypertension who were also initially managed conventionally by bed rest. Atenolol given once daily significantly reduced blood-pressure, prevented proteinuria, and reduced the number of hospital admissions. Loss of(More)
Uteroplacental waveforms in 32 untreated patients with pregnancy-induced hypertension (PIH) were compared with those in 32 carefully matched women with normal pregnancies (alpha = 0.05; beta = 0.80 for 30% difference between groups). Although some of the PIH patients showed high-resistance waveforms, both high and low resistance patterns were obtained from(More)
Doppler velocimetry of the uteroplacental and umbilical arteries provides an opportunity for the safe, reproducible and repeatable study of these circulations and already has led to an increased knowledge of the pathophysiology of pregnancy induced hypertension and intra-uterine growth retardation. This technique, which has only recently been introduced(More)