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The activity of 2', 3'-cyclic nucleotide 3'-phosphohydrolase (CNP, EC 126.96.36.199), a myelin-associated enzyme, was monitored in brain, spinal cord, and sciatic nerve homogenates from tri-o-tolyl phosphate (TOTP) and tri-m-tolyl phosphate (TMTP) treated hens. Atropinized adult White Leghorn hens were orally dosed with TOTP (200 mg/kg) or with TMTP (200 mg/kg).… (More)
Six trace elements were monitored in neural tissue homogenates from White Leghorn hens orally dosed with tri-o-tolyl phosphate (TOTP) or tri-m-tolyl phosphate (TMTP) (200 mg/kg). Treated birds were monitored daily for development of delayed neurotoxicity, and concentrations of calcium, copper, iron, magnesium, manganese, and zinc were measured with atomic… (More)