P. A. Petyunin

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The reac t ion of I with acid chlor ide monoethyloxalate yielded an ethoxalyl der ivat ive (lI) which gave with p r i m a r y alkylamines 78-93% of N(p-R-oxamidobenzenesu l fony l ) -N-n-bu ty l -u rea (III-VIII; Table 1). Sulfamides X and XI were p r epa red by condensing e s t e r II with sulfamides IX in the p resence of sodium methylate [7]. Compounds(More)
Benzonal (III) [4] has been synthesized with the aim of strengthening the anticonvulsive activity of phenobarbital. The virtue of this preparation is the absence of hypnotic action; occasionally benzonal is prescribed in combination with phenobarbital. It has been established that alkylatlon at the nitrogen in phenobarbital reduces the antleonvulsive action(More)
React ions w e r e ca r r i ed out between e s t e r s of p -d ie thy lamin ioprop ion ic (I), f l -ani l inopropionic (1I), f l -p iper idinopropionic diD, and ~ -me thy l f l -morpho l inop rop ion i c (IV) acid and a ry ld imagnesy lamines (V). The a r y l a m i d e s (VI-VIII) we re isolated as hydrochlor ides and the r e m a i n d e r as f r ee bases(More)
Recently, a great deal of attention has been given to the search for biologically active compounds in the ser ies of indole derivat ives [1]. It seemed interest ing to become involved in the investigation of 3,3dialkyloxindoles having dialkylaminoalkyl chains on the nitrogen. This group of compounds has been studied insufficiently f rom a chemical and(More)
The starting oxalic acid arenesulfohydrazide esters (i) were prepared according to [2, 3]. The hydroxylamination reaction of esters I was carried out using an alkaline solution of hydroxylamine. The resulting hydroxamic acid salt (II) was then decomposed with HCI to give the corresponding oxalohydroxamic acid arenesulfohydrazide derivative (III) (Table i).(More)
p, m, and o-Aminobenzenearsonie acids (I-III) and their derivatives possess various chemotherapeutic activities and find use in medicinal pract ice [1, 2]. Continuing investigations [3-5] in this field, we have ca r r i ed out the synthesis of derivatives of oxanilie acids with an arsono group in the phenyl radical and have tested their ant imicrobial(More)
In earlier work [3], we described a method of obtaining esters of benzolactam-N-acetic acids and studied some of their transformations. We were therefore interested in an expansion of these studies, and at the same time to test previously-* and newly-prepared compounds for their anti-inflammatory activity, especially since heterylalkanoic acids and their(More)