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New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis.
- A. Girault, J-P Haelters, +11 authors C. Vandier
- Medicine, Biology
- Current cancer drug targets
- 31 October 2011
Edelfosine is an inhibitor of SK3 channel mediated cell migration. However, this compound bears adverse in vivo side effects. Using cell SK3 dependent cell-migration assay, patch-clamp, (125)I-apamin… Expand
Targeting SKCa channels in cancer: potential new therapeutic approaches.
- A. Girault, J-P Haelters, +5 authors C. Vandier
- Biology, Medicine
- Current medicinal chemistry
- 31 January 2012
Many studies have reported changes in potassium channel expression in many cancers and the involvement of these channels in various stages of cancer progression. By contrast, data concerning SKCa… Expand
Evaluation of the transfection efficacies of quaternary ammonium salts prepared from sophorolipids.
- E. Delbeke, O. Lozach, +5 authors C. Stevens
- Medicine, Chemistry
- Organic & biomolecular chemistry
- 12 April 2016
Five quaternary ammonium amphiphilic compounds were synthesized from sophorolipid 1. These compounds were formulated in aqueous media and some of them (5 and 6) produced well-defined supramolecular… Expand