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New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis.
Edelfosine is an inhibitor of SK3 channel mediated cell migration. However, this compound bears adverse in vivo side effects. Using cell SK3 dependent cell-migration assay, patch-clamp, (125)I-apaminExpand
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Targeting SKCa channels in cancer: potential new therapeutic approaches.
Many studies have reported changes in potassium channel expression in many cancers and the involvement of these channels in various stages of cancer progression. By contrast, data concerning SKCaExpand
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Evaluation of the transfection efficacies of quaternary ammonium salts prepared from sophorolipids.
Five quaternary ammonium amphiphilic compounds were synthesized from sophorolipid 1. These compounds were formulated in aqueous media and some of them (5 and 6) produced well-defined supramolecularExpand
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